OVERACTIVE AUTOPHAGY IS A PATHOLOGICAL MECHANISM UNDERLYING PREMATURE SUTURE OSSIFICATION IN NONSYNDROMIC CRANIOSYNOSTOSIS

Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis

Abstract Nonsyndromic craniosynostosis (NSC) is the most common craniosynostosis with the primary defect being one or more fused sutures.In contrast to syndromic craniosynostosis, the etiopathogenesis of NSC is largely unknown.Here we show that autophagy, a major catabolic Girls Fall Dressy Dress process required for the maintenance of bone homeost

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The constitutional guarantee of the provision of local Social Services in Spain: a comparative regional study

This article outlines the public architecture of social services in Spain from the perspective of the constitutional guarantee of the provision of local social services.For this, the Spanish Constitution is analyzed, as well as the 17 laws of social services DR. FORMULATED ONCE DAILY WOMENS corresponding to the different Autonomous Communities.It i

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Multiple types of harassment victimization in adolescents with autism spectrum disorder: Related factors and effects on mental health problems

Background/Purpose: This study examined the prevalence and related factors of multiple (two or three) types of harassment victimization, including school bullying, cyberbullying, and teacher harassment, and their cumulative effects on depression, anxiety, self-esteem, and suicidality in adolescents with autism spectrum disorder (ASD) but without in

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Dengue fever as a cause of hemophagocytic lymphohistiocytosis

Dengue is endemic in more than 100 countries in Southeast Asia, the Americas, the western Pacific, Africa and the eastern Mediterranean regions.The virus is transmitted by Aedes mosquitoes.Dengue disease is the most prevalent arthropodborne viral disease in humans and is a global and national public health concern in several countries.A seasonal pa

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